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InvestigationsAltered prothrombin timeprolongation and reductionin patients concomitantly treated with warfarin and increased blood creatine phosphokinase have been reported.
In vitro studies with human liver microsomes showed that terbinafine does not inhibit the metabolism of tolbutamideethinylestradiolethoxycoumarincyclosporinecisapride and fluvastatinIn vivo drug-drug interaction studies conducted in healthy volunteer subjects showed that terbinafine does not affect the clearance of antipyrine or digoxinTerbinafine decreases the clearance of caffeine by 19Terbinafine increases the clearance of cyclosporine by 15
Measurement of serum transaminasesALT and ASTis advised for all patients before taking Lamisil Tablets.
Take Lamisil exactly as prescribed by your doctorFollow all directions on your prescription labelDo not take this medicine in larger or smaller amounts or for longer than recommended.
Idiosyncratic and symptomatic hepatic injurymore rarelycases of liver failuresome leading to death or liver transplant.
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the active ingredient in lamisil cream is the antifungal substance terbinafine which fights infection by preventing fungus from continuing to grow and then kill it.